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Hyunho Lee, Matteo Massaro, Nourhan Abdelfattah, Gherardo Baudo, Haoran Liu, Kyuson Yun, Elvin Blanco
TL;DR
This paper explores how increasing NRF1 helps prevent mitochondrial issues and cell aging in stem cells.
Contribution
The study shows NRF1 induction as a novel strategy to counter mitochondrial dysfunction and senescence in mesenchymal stem cells.
Findings
NRF1 induction improves mitochondrial function in mesenchymal stem cells.
Increased NRF1 levels delay cellular senescence in these cells.
Abstract
The cover image is based on the article Nuclear respiratory factor‐1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells by Hyunho Lee et al., https://doi.org/10.1111/acel.14446.
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Taxonomy
TopicsAdipose Tissue and Metabolism · Mesenchymal stem cell research · GDF15 and Related Biomarkers