# Additional Cover

## TL;DR

This paper explores how increasing NRF1 helps prevent mitochondrial issues and cell aging in stem cells.

## Contribution

The study shows NRF1 induction as a novel strategy to counter mitochondrial dysfunction and senescence in mesenchymal stem cells.

## Key findings

- NRF1 induction improves mitochondrial function in mesenchymal stem cells.
- Increased NRF1 levels delay cellular senescence in these cells.

## Abstract

The cover image is based on the article Nuclear respiratory factor‐1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells by Hyunho Lee et al., https://doi.org/10.1111/acel.14446.