Progress in hematopoietic stem cell transplantation for acute myeloid leukemia
晓璐 朱, 晓军 黄, 昱 王
TL;DR
This paper reviews recent advances in hematopoietic stem cell transplantation for treating acute myeloid leukemia.
Contribution
The paper provides an updated overview of HSCT applications, donor selection, and novel strategies to improve outcomes in AML.
Findings
HSCT remains a critical treatment for AML despite new drug developments.
New strategies for preventing relapse and improving outcomes in refractory AML are discussed.
Optimized HSCT techniques for elderly AML patients are reviewed.
Abstract
急性髓系白血病（AML）是髓系造血干/祖细胞恶性疾病，尽管近年来血液疾病领域新药层出不穷，造血干细胞移植（HSCT）在血液疾病领域中的地位仍不可取代。本文就HSCT在AML的适应证调整和供者选择、预处理方案的更新、移植后复发的新型预防策略、新型靶向药物、免疫治疗联合HSCT改善复发/难治AML患者预后以及老年AML的移植技术优化进行综述。
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsAcute Myeloid Leukemia Research