# Progress in hematopoietic stem cell transplantation for acute myeloid leukemia

**Authors:** 晓璐 朱, 晓军 黄, 昱 王

PMC · DOI: 10.3760/cma.j.cn121090-20240422-00157 · 2025-02-01

## TL;DR

This paper reviews recent advances in hematopoietic stem cell transplantation for treating acute myeloid leukemia.

## Contribution

The paper provides an updated overview of HSCT applications, donor selection, and novel strategies to improve outcomes in AML.

## Key findings

- HSCT remains a critical treatment for AML despite new drug developments.
- New strategies for preventing relapse and improving outcomes in refractory AML are discussed.
- Optimized HSCT techniques for elderly AML patients are reviewed.

## Abstract

急性髓系白血病（AML）是髓系造血干/祖细胞恶性疾病，尽管近年来血液疾病领域新药层出不穷，造血干细胞移植（HSCT）在血液疾病领域中的地位仍不可取代。本文就HSCT在AML的适应证调整和供者选择、预处理方案的更新、移植后复发的新型预防策略、新型靶向药物、免疫治疗联合HSCT改善复发/难治AML患者预后以及老年AML的移植技术优化进行综述。

## Linked entities

- **Diseases:** acute myeloid leukemia (MONDO:0015667)

## Full-text entities

- **Diseases:** AML (MESH:D015470)

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Source: https://tomesphere.com/paper/PMC11951221