Successful Resolution of Eruptive Xanthomas in Severe Hypertriglyceridemia With Plasmapheresis
Arūnas Petkevičius, Robertina Cibulskaitė, Ugnė Janonytė, Jurgita Makštienė, Birutė Žilaitienė
TL;DR
A 47-year-old woman with severe skin lesions and high triglycerides saw full recovery after plasmapheresis treatment.
Contribution
Demonstrates plasmapheresis as an effective treatment for eruptive xanthomas in severe hypertriglyceridemia.
Findings
Plasmapheresis led to complete resolution of eruptive xanthomas.
Triglyceride levels normalized after six plasmapheresis sessions.
Treatment was effective despite multiple comorbidities.
Abstract
Eruptive xanthomatosis, characterised by yellowish skin papules, is often associated with hypertriglyceridemia and can signal underlying systemic conditions such as uncontrolled diabetes. Here, we present the case of a 47-year-old woman with eruptive xanthomas and severe hypertriglyceridemia. Taking into consideration the multiple comorbidities, including type 2 diabetes, obesity, and a history of acute pancreatitis, the patient was treated with six courses of plasmapheresis, leading to complete resolution of the lesions and normal triglyceride (TG) levels.
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Taxonomy
TopicsLipid metabolism and disorders · Erythrocyte Function and Pathophysiology · Caveolin-1 and cellular processes