# Successful Resolution of Eruptive Xanthomas in Severe Hypertriglyceridemia With Plasmapheresis

## TL;DR

A 47-year-old woman with severe skin lesions and high triglycerides saw full recovery after plasmapheresis treatment.

## Contribution

Demonstrates plasmapheresis as an effective treatment for eruptive xanthomas in severe hypertriglyceridemia.

## Key findings

- Plasmapheresis led to complete resolution of eruptive xanthomas.
- Triglyceride levels normalized after six plasmapheresis sessions.
- Treatment was effective despite multiple comorbidities.

## Abstract

Eruptive xanthomatosis, characterised by yellowish skin papules, is often associated with hypertriglyceridemia and can signal underlying systemic conditions such as uncontrolled diabetes. Here, we present the case of a 47-year-old woman with eruptive xanthomas and severe hypertriglyceridemia. Taking into consideration the multiple comorbidities, including type 2 diabetes, obesity, and a history of acute pancreatitis, the patient was treated with six courses of plasmapheresis, leading to complete resolution of the lesions and normal triglyceride (TG) levels.