Featured Cover
Akash Kumar Singh, Ila Joshi, Neeharika M. N. Reddy, Sushmitha S. Purushotham, M. Eswaramoorthy, Madavan Vasudevan, Sourav Banerjee, James P. Clement, Tapas K. Kundu
TL;DR
This study shows that epigenetic modulation can help fix brain development issues in mice with a specific genetic mutation.
Contribution
The research introduces a novel epigenetic approach to address neurodevelopmental deficits in Syngap1+/− mice.
Findings
Epigenetic modulation rescued cognitive and behavioral deficits in Syngap1+/− mice.
The treatment improved synaptic plasticity and brain function in the affected mice.
Abstract
The cover image is based on the article Epigenetic modulation rescues neurodevelopmental deficits in Syngap1+/−; mice by Akash Kumar Singh et al.,https://doi.org/10.1111/acel.14408
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsEpigenetics and DNA Methylation · Nuclear Receptors and Signaling · Genetics and Neurodevelopmental Disorders