This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: TMEM107 Inhibits EMT and Invasion of NSCLC Through Regulating the Hedgehog Pathway
TL;DR
This retracted paper claimed that TMEM107 inhibits cancer cell invasion in lung cancer by affecting a specific pathway.
Contribution
The paper originally proposed a novel mechanism involving TMEM107 and the Hedgehog pathway in NSCLC.
Findings
TMEM107 was reported to inhibit EMT and invasion in NSCLC cells.
The Hedgehog pathway was suggested to mediate TMEM107's effects.
Duplicated images in figures led to retraction of the study.
Abstract
RETRACTION: XuH. , DunS. , GaoY. , MingJ. , HuiL. , and QiuX. , “TMEM107 Inhibits EMT and Invasion of NSCLC Through Regulating the Hedgehog Pathway,” Thoracic Cancer 12, no. 1 (2021): 79–89, 10.1111/1759-7714.13715.33124203 PMC7779196 The above article, published online on 29 October 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Tateaki Naito; and John Wiley & Sons Australia, Ltd. The retraction has been agreed following concerns raised by a third party about duplicated images in Figures 3i and 4e. The authors acknowledge this error and note that Figure 4e inadvertently included images from the si‐TMEM07 and pNC groups of Figure 3i for the A549 cells. Therefore, the article must be retracted.
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Taxonomy
TopicsHedgehog Signaling Pathway Studies · Cancer-related gene regulation · Cholangiocarcinoma and Gallbladder Cancer Studies
RETRACTION:
H. Xu , S. Dun , Y. Gao , J. Ming , L. Hui , and X. Qiu , “TMEM107 Inhibits EMT and Invasion of NSCLC Through Regulating the Hedgehog Pathway,” Thoracic Cancer 12, no. 1 (2021): 79–89, 10.1111/1759-7714.13715.33124203 PMC7779196
The above article, published online on 29 October 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Tateaki Naito; and John Wiley & Sons Australia, Ltd. The retraction has been agreed following concerns raised by a third party about duplicated images in Figures 3i and 4e. The authors acknowledge this error and note that Figure 4e inadvertently included images from the si‐TMEM07 and pNC groups of Figure 3i for the A549 cells. Therefore, the article must be retracted.