A21 MINIMAL MIMETIC MATRICES DRIVE COLONIC ORGANOIDS TOWARD A DISEASE-ASSOCIATED STRESS RESPONSE

TL;DR

This study explores how minimal mimetic matrices influence colonic organoids to adopt a disease-related stress response.

Contribution

The research introduces a novel approach using minimal mimetic matrices to model disease-associated responses in colonic organoids.

Findings

Colonic organoids respond to minimal mimetic matrices with a stress response.

The stress response resembles disease-associated patterns.

This method provides insights into disease modeling using simplified matrices.

Abstract

NOT PUBLISHED AT THE AUTHOR’S REQUEST

Please acknowledge the funding agency below

Funding Agencies: CIHR