# A21 MINIMAL MIMETIC MATRICES DRIVE COLONIC ORGANOIDS TOWARD A DISEASE-ASSOCIATED STRESS RESPONSE

## TL;DR

This study explores how minimal mimetic matrices influence colonic organoids to adopt a disease-related stress response.

## Contribution

The research introduces a novel approach using minimal mimetic matrices to model disease-associated responses in colonic organoids.

## Key findings

- Colonic organoids respond to minimal mimetic matrices with a stress response.
- The stress response resembles disease-associated patterns.
- This method provides insights into disease modeling using simplified matrices.

## Abstract

NOT PUBLISHED AT THE AUTHOR’S REQUEST

Please acknowledge the funding agency below

Funding Agencies: CIHR

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Source: https://tomesphere.com/paper/PMC11807519