This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: LncRNA CCAT2 Promotes the Proliferation and Metastasis of Colorectal Cancer Through Activation of the ERK and Wnt Signaling Pathways by Regulating GNB2 Expression
TL;DR
This retracted study claimed that the lncRNA CCAT2 promotes colorectal cancer growth and spread by activating ERK and Wnt pathways through GNB2 regulation.
Contribution
The paper proposed a novel mechanism involving CCAT2 and GNB2 in colorectal cancer progression.
Findings
CCAT2 was reported to promote cancer cell proliferation and metastasis.
ERK and Wnt signaling pathways were said to be activated via GNB2 regulation by CCAT2.
Abstract
RETRACTION: J. Tian, X. Cao, Z. Jiang, J. Wang, W. Fan, S. Zhang, S. Zhao, and J. Sun, “LncRNA CCAT2 Promotes the Proliferation and Metastasis of Colorectal Cancer Through Activation of the ERK and Wnt Signaling Pathways by Regulating GNB2 Expression,” Cancer Medicine 13, no. 17 (2024): e70169, https://doi.org/10.1002/cam4.70169. The above article, published online on 03 September 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Stephen Tait; and John Wiley & Sons Ltd. The authors reported to the journal that a third party had detected multiple overlapping panels within and between Figures 2 and 7 in this article. The authors further stated that, upon reviewing the published article, they discovered multiple issues related to image overlap and redundancy. All parties agree that the…
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Taxonomy
TopicsCancer-related molecular mechanisms research · Colorectal Cancer Treatments and Studies · Tannin, Tannase and Anticancer Activities
RETRACTION: J. Tian, X. Cao, Z. Jiang, J. Wang, W. Fan, S. Zhang, S. Zhao, and J. Sun, “LncRNA CCAT2 Promotes the Proliferation and Metastasis of Colorectal Cancer Through Activation of the ERK and Wnt Signaling Pathways by Regulating GNB2 Expression,” Cancer Medicine 13, no. 17 (2024): e70169, https://doi.org/10.1002/cam4.70169.
The above article, published online on 03 September 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the authors; the journal Editor‐in‐Chief, Stephen Tait; and John Wiley & Sons Ltd. The authors reported to the journal that a third party had detected multiple overlapping panels within and between Figures 2 and 7 in this article. The authors further stated that, upon reviewing the published article, they discovered multiple issues related to image overlap and redundancy. All parties agree that the overlapping and duplicated images constitute a major error in the article and it must be retracted.