Mysterious Keratitis Responding Favorably to Antiviral Therapy
Surbhi A Chodvadiya, Megha R Kotecha, Varsha Manade, Gufran A Kamdar, Jessica Sangwan

TL;DR
A 35-year-old patient with unexplained corneal inflammation improved rapidly with antiviral treatment, suggesting a hidden viral cause.
Contribution
Highlights the potential role of antiviral therapy in atypical keratitis cases with unknown causes.
Findings
Empirical antiviral treatment led to rapid symptom resolution in a patient with unexplained keratitis.
The case suggests viral etiologies should be considered even in atypical presentations of corneal inflammation.
Abstract
Keratitis, characterized by inflammation of the cornea, presents a diagnostic challenge, particularly when the etiology remains elusive. Here, we report a perplexing case of keratitis in a 35-year-old patient with no identifiable risk factors or predisposing conditions. Despite the initial uncertainty, empirical treatment with antiviral medications led to a rapid resolution of symptoms and improvement in corneal health. This case underscores the importance of considering viral etiologies even in cases with atypical presentations and highlights the potential efficacy of antiviral therapy in such scenarios. Further investigation is needed to understand the underlying causes and improve treatment approaches for similar cases of unexplained keratitis.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsOcular Infections and Treatments · Ocular Surface and Contact Lens · Ocular Diseases and Behçet’s Syndrome
