# Mysterious Keratitis Responding Favorably to Antiviral Therapy

**Authors:** Surbhi A Chodvadiya, Megha R Kotecha, Varsha Manade, Gufran A Kamdar, Jessica Sangwan

PMC · DOI: 10.7759/cureus.66384 · 2024-08-07

## TL;DR

A 35-year-old patient with unexplained corneal inflammation improved rapidly with antiviral treatment, suggesting a hidden viral cause.

## Contribution

Highlights the potential role of antiviral therapy in atypical keratitis cases with unknown causes.

## Key findings

- Empirical antiviral treatment led to rapid symptom resolution in a patient with unexplained keratitis.
- The case suggests viral etiologies should be considered even in atypical presentations of corneal inflammation.

## Abstract

Keratitis, characterized by inflammation of the cornea, presents a diagnostic challenge, particularly when the etiology remains elusive. Here, we report a perplexing case of keratitis in a 35-year-old patient with no identifiable risk factors or predisposing conditions. Despite the initial uncertainty, empirical treatment with antiviral medications led to a rapid resolution of symptoms and improvement in corneal health. This case underscores the importance of considering viral etiologies even in cases with atypical presentations and highlights the potential efficacy of antiviral therapy in such scenarios. Further investigation is needed to understand the underlying causes and improve treatment approaches for similar cases of unexplained keratitis.

## Linked entities

- **Diseases:** keratitis (MONDO:0003085)

## Full-text entities

- **Diseases:** inflammation of the cornea (MESH:D007249), Keratitis (MESH:D007634)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11379056/full.md

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Source: https://tomesphere.com/paper/PMC11379056