This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: Microrna‐379 Suppresses Osteosarcoma Progression by Targeting PDK1
TL;DR
This retracted paper claimed that microRNA-379 suppresses osteosarcoma by targeting PDK1, but image duplications led to its retraction.
Contribution
The paper originally proposed a novel mechanism of microRNA-379 in suppressing osteosarcoma progression via PDK1.
Findings
MicroRNA-379 was reported to inhibit osteosarcoma progression by targeting PDK1.
Image duplication issues in figures led to the retraction of the study.
The co-author J. Shen denied involvement in the research and its publication.
Abstract
RETRACTION: Li, Z., Shen, J., Chan, M. T. V., and Wu, W. K. K. (2017). Microrna‐379 Suppresses Osteosarcoma Progression by Targeting PDK1. Journal of Cellular and Molecular Medicine, 21(2), 315–323. https://doi.org/10.1111/jcmm.12966 The above article, published online on 25 October 2016 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor‐in‐Chief, Stefan Constantinescu; The Foundation for Cellular and Molecular Medicine and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation into concerns raised by a third party, which revealed inappropriate duplications of image panels (Figures 2D, 3, 4G, 6A and F) within the article and between this and other articles that were previously published or published shortly after in a different scientific context. The authors were unable to provide a satisfactory…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCircular RNAs in diseases · Cancer-related molecular mechanisms research · interferon and immune responses
RETRACTION: Li, Z., Shen, J., Chan, M. T. V., and Wu, W. K. K. (2017). Microrna‐379 Suppresses Osteosarcoma Progression by Targeting PDK1. Journal of Cellular and Molecular Medicine, 21(2), 315–323. https://doi.org/10.1111/jcmm.12966
The above article, published online on 25 October 2016 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor‐in‐Chief, Stefan Constantinescu; The Foundation for Cellular and Molecular Medicine and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation into concerns raised by a third party, which revealed inappropriate duplications of image panels (Figures 2D, 3, 4G, 6A and F) within the article and between this and other articles that were previously published or published shortly after in a different scientific context. The authors were unable to provide a satisfactory explanation and the provided raw data could not explain the identified issues, which has led the editors to lose confidence in the data presented. Therefore, the editors consider the conclusions substantially compromised and are retracting the paper. The co‐author, J. Shen stated that they were not involved in this research and had no knowledge about its publication, and their correspondence email address was added without their consent. The authors, including Z. Li who submitted the manuscript, were informed of the decision to retract but did not respond to the retraction or the retraction wording.