Guillain-Barre syndrome after allogeneic hematopoietic stem cell transplantation: a case report and literature review

TL;DR

A rare case of Guillain-Barre syndrome after a stem cell transplant is reported, highlighting the importance of early diagnosis and treatment.

Contribution

This paper presents a rare case of Guillain-Barre syndrome following allogeneic stem cell transplantation in China.

Findings

A patient developed Guillain-Barre syndrome five months after a stem cell transplant.

High-dose intravenous immunoglobulin treatment led to muscle strength recovery.

Early diagnosis and treatment improved the patient's prognosis.

Abstract

异基因造血干细胞移植后合并吉兰-巴雷综合征较为罕见，国内报道很少。吉兰-巴雷综合征发病急，严重威胁患者生命，需尽早诊断及治疗。1例急性髓系白血病患者行异基因造血干细胞移植后5个月余，合并迟发急性肠道移植物抗宿主病后逐渐出现四肢肌无力、眼球运动受限，经脑脊液、肌电图等检查，明确诊断吉兰-巴雷综合征，经大剂量静脉免疫球蛋白治疗，肌力逐渐恢复，预后良好。