# Guillain-Barre syndrome after allogeneic hematopoietic stem cell transplantation: a case report and literature review

**Authors:** 亚军 石, 英 汉, 莹 王, 芮 周, 瑞 宋, 东锋 毛, 瑞 葸, 海 白, 涛 吴

PMC · DOI: 10.3760/cma.j.cn121090-20231020-00222 · 2024-05-01

## TL;DR

A rare case of Guillain-Barre syndrome after a stem cell transplant is reported, highlighting the importance of early diagnosis and treatment.

## Contribution

This paper presents a rare case of Guillain-Barre syndrome following allogeneic stem cell transplantation in China.

## Key findings

- A patient developed Guillain-Barre syndrome five months after a stem cell transplant.
- High-dose intravenous immunoglobulin treatment led to muscle strength recovery.
- Early diagnosis and treatment improved the patient's prognosis.

## Abstract

异基因造血干细胞移植后合并吉兰-巴雷综合征较为罕见，国内报道很少。吉兰-巴雷综合征发病急，严重威胁患者生命，需尽早诊断及治疗。1例急性髓系白血病患者行异基因造血干细胞移植后5个月余，合并迟发急性肠道移植物抗宿主病后逐渐出现四肢肌无力、眼球运动受限，经脑脊液、肌电图等检查，明确诊断吉兰-巴雷综合征，经大剂量静脉免疫球蛋白治疗，肌力逐渐恢复，预后良好。

## Linked entities

- **Diseases:** Guillain-Barre syndrome (MONDO:0016218), acute myeloid leukemia (MONDO:0015667), graft-versus-host disease (MONDO:0013730)

## Full-text entities

- **Diseases:** muscle weakness (MESH:D018908), intestinal graft-versus-host disease (MESH:D006086), limited eye movement (MESH:D015835), Guillain-Barre syndrome (MESH:D020275), acute myeloid leukemia (MESH:D015470)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11270495