Squamous Metaplasia in a Schwannoma: A Unique Histologic Finding

TL;DR

A schwannoma tumor in a 61-year-old woman showed an unusual feature of squamous metaplasia, a finding not previously reported in medical literature.

Contribution

This paper reports the first documented case of squamous metaplasia within a schwannoma.

Findings

A schwannoma resected from a 61-year-old female contained squamous metaplasia.

This histologic finding has not been previously reported in the literature.

The finding may help pathologists recognize atypical presentations of schwannomas.

Abstract

Schwannomas are benign peripheral nerve sheath tumors that originate from Schwann cells and characteristically display a biphasic appearance of compact hypercellular and myxoid hypocellular areas, named Antoni A and Antoni B areas, respectively. While most schwannomas arise sporadically, they can be associated with familial tumor syndromes such as neurofibromatosis type 2 and Carney complex. Herein, we report a case of a 61-year-old female who had a schwannoma resected from her upper extremity that later revealed a focus of squamous metaplasia associated with the schwannoma, a finding that has not yet been reported in the literature. This unique finding may aid pathologists in the future when confronted with such an atypical presentation in a schwannoma.

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