Lymphoid follicular hyperplasia arising from the chest wall presenting as a substantial mass

TL;DR

A rare benign lymphoproliferative disease called lymphoid follicular hyperplasia was found on a woman's chest wall and confirmed through surgery.

Contribution

This is the first reported case of lymphoid follicular hyperplasia originating from the chest wall.

Findings

Lymphoid follicular hyperplasia was diagnosed after surgical resection of a chest wall mass.

The case highlights the importance of considering this condition in differential diagnoses for similar benign tumors.

Abstract

Lymphoid follicular hyperplasia (LFH) is a benign lymphoproliferative disease. Although it can occur within the thoracic cavity, LFH originating from the chest wall has not been reported. A 79‐year‐old woman was incidentally found to have a well‐defined mass on the left posterior chest wall during a preoperative examination for aortic valve replacement. The mass had slowly grown over 6 years. Thoracoscopic surgical resection was performed without complications. Pathological examination ruled out lymphoproliferative diseases, such as Castleman disease or malignant lymphoma, and a diagnosis of LFH was made. Although LFH generally has a good prognosis, surgical resection is recommended for diagnostic and therapeutic purposes owing to the possibility of malignancy masquerading as a reactive lesion. This is the first report of an LFH arising from the chest wall with imaging findings similar to other benign tumours. Its potential as a differential diagnosis for tumours with similar imaging findings is highlighted.

Lymphoid follicular hyperplasia, a rare benign lymphoproliferative disease, was found on the chest wall of a 79‐year‐old woman. Surgical resection confirmed the diagnosis, emphasizing lymphoid follicular hyperplasia as a potential alternative diagnosis for similar benign tumours.

Figures