# Lymphoid follicular hyperplasia arising from the chest wall presenting as a substantial mass

## TL;DR

A rare benign lymphoproliferative disease called lymphoid follicular hyperplasia was found on a woman's chest wall and confirmed through surgery.

## Contribution

This is the first reported case of lymphoid follicular hyperplasia originating from the chest wall.

## Key findings

- Lymphoid follicular hyperplasia was diagnosed after surgical resection of a chest wall mass.
- The case highlights the importance of considering this condition in differential diagnoses for similar benign tumors.

## Abstract

Lymphoid follicular hyperplasia (LFH) is a benign lymphoproliferative disease. Although it can occur within the thoracic cavity, LFH originating from the chest wall has not been reported. A 79‐year‐old woman was incidentally found to have a well‐defined mass on the left posterior chest wall during a preoperative examination for aortic valve replacement. The mass had slowly grown over 6 years. Thoracoscopic surgical resection was performed without complications. Pathological examination ruled out lymphoproliferative diseases, such as Castleman disease or malignant lymphoma, and a diagnosis of LFH was made. Although LFH generally has a good prognosis, surgical resection is recommended for diagnostic and therapeutic purposes owing to the possibility of malignancy masquerading as a reactive lesion. This is the first report of an LFH arising from the chest wall with imaging findings similar to other benign tumours. Its potential as a differential diagnosis for tumours with similar imaging findings is highlighted.

Lymphoid follicular hyperplasia, a rare benign lymphoproliferative disease, was found on the chest wall of a 79‐year‐old woman. Surgical resection confirmed the diagnosis, emphasizing lymphoid follicular hyperplasia as a potential alternative diagnosis for similar benign tumours.