U-Shaped Relationship Between Fibrinogen Level and 10-year Mortality in Patients With Acute Coronary Syndrome: Prospective Cohort Study
Yi ming Li, Yuheng Jia, Lin Bai, Bosen Yang, Mao Chen, Yong Peng
TL;DR
High or low fibrinogen levels are linked to higher death risk in heart patients over 10 years.
Contribution
A U-shaped relationship between fibrinogen levels and mortality in ACS patients is identified.
Findings
Fibrinogen is an independent risk factor for 10-year mortality in ACS patients.
A U-shaped nonlinear relationship exists between fibrinogen levels and mortality.
Long-term anti-inflammatory treatment may be beneficial for ACS patients.
Abstract
This study demonstrated that fibrinogen is an independent risk factor for 10-year mortality in patients with acute coronary syndrome (ACS), with a U-shaped nonlinear relationship observed between the two. These findings underscore the importance of monitoring fibrinogen levels and the consideration of long-term anti-inflammatory treatment in the clinical management of patients with ACS.
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Taxonomy
TopicsBlood properties and coagulation · Acute Myocardial Infarction Research · Adipokines, Inflammation, and Metabolic Diseases