# U-Shaped Relationship Between Fibrinogen Level and 10-year Mortality in Patients With Acute Coronary Syndrome: Prospective Cohort Study

## TL;DR

High or low fibrinogen levels are linked to higher death risk in heart patients over 10 years.

## Contribution

A U-shaped relationship between fibrinogen levels and mortality in ACS patients is identified.

## Key findings

- Fibrinogen is an independent risk factor for 10-year mortality in ACS patients.
- A U-shaped nonlinear relationship exists between fibrinogen levels and mortality.
- Long-term anti-inflammatory treatment may be beneficial for ACS patients.

## Abstract

This study demonstrated that fibrinogen is an independent risk factor for 10-year mortality in patients with acute coronary syndrome (ACS), with a U-shaped nonlinear relationship observed between the two. These findings underscore the importance of monitoring fibrinogen levels and the consideration of long-term anti-inflammatory treatment in the clinical management of patients with ACS.