Correction: Reduced protein-coding transcript diversity in severe dengue emphasises the role of alternative splicing
Priyanka Mehta, Chinky Shiu Chen Liu, Sristi Sinha, Ramakant Mohite, Smriti Arora, Partha Chattopadhyay, Sandeep Budhiraja, Bansidhar Tarai, Rajesh Pandey
TL;DR
Severe dengue reduces diversity of protein-coding transcripts, highlighting the importance of alternative splicing in immune response.
Contribution
Identifies reduced transcript diversity and altered splicing in severe dengue, suggesting new therapeutic targets.
Findings
Transcriptomic analysis shows altered immune pathways in severe dengue.
Reduced transcript diversity is observed in severe cases.
Alternative splicing plays a key role in immune response changes.
Abstract
Transcriptomic analysis of dengue-infected patients reveals altered immune response pathways, transcript diversity, and splicing efficiency, underscoring potential therapeutic targets for treatment.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMosquito-borne diseases and control · Studies on Chitinases and Chitosanases