# Correction: Reduced protein-coding transcript diversity in severe dengue emphasises the role of alternative splicing

**Authors:** Priyanka Mehta, Chinky Shiu Chen Liu, Sristi Sinha, Ramakant Mohite, Smriti Arora, Partha Chattopadhyay, Sandeep Budhiraja, Bansidhar Tarai, Rajesh Pandey

PMC · DOI: 10.26508/lsa.202402882 · 2024-06-14

## TL;DR

Severe dengue reduces diversity of protein-coding transcripts, highlighting the importance of alternative splicing in immune response.

## Contribution

Identifies reduced transcript diversity and altered splicing in severe dengue, suggesting new therapeutic targets.

## Key findings

- Transcriptomic analysis shows altered immune pathways in severe dengue.
- Reduced transcript diversity is observed in severe cases.
- Alternative splicing plays a key role in immune response changes.

## Abstract

Transcriptomic analysis of dengue-infected patients reveals altered immune response pathways, transcript diversity, and splicing efficiency, underscoring potential therapeutic targets for treatment.

## Linked entities

- **Diseases:** dengue (MONDO:0005502)

## Full-text entities

- **Diseases:** dengue (MESH:D003715)

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Source: https://tomesphere.com/paper/PMC11178938