The Clinical and Histological Intersection of Cardiac Sarcoidosis and Giant Cell Myocarditis
Toishi Sharma, Kramer Wahlberg, Friederike Keating, Ahmed Harhash, Leslie T Cooper
TL;DR
This paper presents a case where a heart condition showed features of both cardiac sarcoidosis and giant cell myocarditis, highlighting challenges in diagnosing and managing overlapping diseases.
Contribution
The case demonstrates an intermediate clinicohistologic phenotype between cardiac sarcoidosis and giant cell myocarditis.
Findings
The patient exhibited heart block and ventricular tachycardia.
Cardiac MRI, FDG-PET, and biopsy revealed overlapping features of CS and GCM.
The case highlights diagnostic and management challenges in overlapping cardiac conditions.
Abstract
The clinical and imaging features of cardiac sarcoidosis (CS) and giant cell myocarditis (GCM) are occasionally indistinguishable. This is a case of heart block and ventricular tachycardia where cardiac MRI, fluorodeoxyglucose positron emission tomography (FDG-PET) and biopsy revealed intermediate clinicohistologic phenotype between CS and GCM. This highlights gaps in the management of overlap conditions.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsSarcoidosis and Beryllium Toxicity Research · Viral Infections and Immunology Research · Vasculitis and related conditions