Suprasellar pilocytic astrocytoma with leptomeningeal dissemination
Siti S. Mohamad Zaini, Hilwati Hashim, Emy S. Rosani, Nor S. Bakar, Suryati Mohd Yusoff
TL;DR
This paper describes a rare case of a low-grade brain tumor spreading to the meninges without becoming more aggressive over time.
Contribution
The novelty lies in documenting leptomeningeal dissemination in a WHO Grade I suprasellar pilocytic astrocytoma without tumor upgrading.
Findings
Leptomeningeal nodules progressed over time without evidence of tumor upgrading.
The tumor remained classified as WHO Grade I despite dissemination.
This case adds to the growing literature on rare manifestations of pilocytic astrocytoma.
Abstract
Leptomeningeal dissemination is a rare manifestation of pilocytic astrocytoma. It may occur with higher-grade tumours like medulloblastoma, ependymoma and high-grade glioma, but is extremely rare with low-grade glioma. There has been a growing number of reported cases documenting leptomeningeal dissemination of pilocytic astrocytoma in the medical literature. Description of a World Health Organization (WHO) Grade I suprasellar pilocytic astrocytoma with leptomeningeal dissemination in the brain and spinal cord which showed progression of the leptomeningeal nodules without tumour upgrading on long-term follow-up.
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Taxonomy
TopicsGlioma Diagnosis and Treatment · Vascular Malformations Diagnosis and Treatment · Epilepsy research and treatment