# Suprasellar pilocytic astrocytoma with leptomeningeal dissemination

**Authors:** Siti S. Mohamad Zaini, Hilwati Hashim, Emy S. Rosani, Nor S. Bakar, Suryati Mohd Yusoff

PMC · DOI: 10.4102/sajr.v28i1.2876 · 2024-05-27

## TL;DR

This paper describes a rare case of a low-grade brain tumor spreading to the meninges without becoming more aggressive over time.

## Contribution

The novelty lies in documenting leptomeningeal dissemination in a WHO Grade I suprasellar pilocytic astrocytoma without tumor upgrading.

## Key findings

- Leptomeningeal nodules progressed over time without evidence of tumor upgrading.
- The tumor remained classified as WHO Grade I despite dissemination.
- This case adds to the growing literature on rare manifestations of pilocytic astrocytoma.

## Abstract

Leptomeningeal dissemination is a rare manifestation of pilocytic astrocytoma. It may occur with higher-grade tumours like medulloblastoma, ependymoma and high-grade glioma, but is extremely rare with low-grade glioma. There has been a growing number of reported cases documenting leptomeningeal dissemination of pilocytic astrocytoma in the medical literature.

Description of a World Health Organization (WHO) Grade I suprasellar pilocytic astrocytoma with leptomeningeal dissemination in the brain and spinal cord which showed progression of the leptomeningeal nodules without tumour upgrading on long-term follow-up.

## Linked entities

- **Diseases:** pilocytic astrocytoma (MONDO:0004000)

## Full-text entities

- **Diseases:** glioma (MESH:D005910), ependymoma (MESH:D004806), pilocytic astrocytoma (MESH:D001254), medulloblastoma (MESH:D008527), tumour (MESH:D009369)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11151406/full.md

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Source: https://tomesphere.com/paper/PMC11151406