Unveiling the Unlikely: Extraskeletal Ewing Sarcoma Masquerading as Gastrointestinal Bleeding

TL;DR

A rare case of Ewing sarcoma, typically a bone cancer, presented as gastrointestinal bleeding and was successfully treated after four years of follow-up.

Contribution

This case highlights the unusual presentation of extraskeletal Ewing sarcoma as gastrointestinal bleeding.

Findings

Ewing sarcoma can present extra-skeletally, mimicking gastrointestinal conditions.

The tumor was resected and managed without further treatment, with no disease recurrence after four years.

Abstract

While Ewing sarcoma is traditionally a malignant tumor of bone, it may uncommonly present extra-skeletally, leading to an array of puzzling presentations depending on the tissue involved. Here, we describe the case of a 66-year-old man who presented to the primary care office for evaluation of intermittent melena. He ultimately underwent capsule endoscopy and developed a secondary small bowel obstruction, unveiling his neoplasm. The tumor was then resected and managed with surveillance only, and the patient remains without evidence of disease after four years of follow-up.

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