# Unveiling the Unlikely: Extraskeletal Ewing Sarcoma Masquerading as Gastrointestinal Bleeding

**Authors:** Bryan M Greenfield, Madeleine A Wilson, Kyle J Schulte, Stephen Silverstein

PMC · DOI: 10.7759/cureus.57109 · 2024-03-28

## TL;DR

A rare case of Ewing sarcoma, typically a bone cancer, presented as gastrointestinal bleeding and was successfully treated after four years of follow-up.

## Contribution

This case highlights the unusual presentation of extraskeletal Ewing sarcoma as gastrointestinal bleeding.

## Key findings

- Ewing sarcoma can present extra-skeletally, mimicking gastrointestinal conditions.
- The tumor was resected and managed without further treatment, with no disease recurrence after four years.

## Abstract

While Ewing sarcoma is traditionally a malignant tumor of bone, it may uncommonly present extra-skeletally, leading to an array of puzzling presentations depending on the tissue involved. Here, we describe the case of a 66-year-old man who presented to the primary care office for evaluation of intermittent melena. He ultimately underwent capsule endoscopy and developed a secondary small bowel obstruction, unveiling his neoplasm. The tumor was then resected and managed with surveillance only, and the patient remains without evidence of disease after four years of follow-up.

## Linked entities

- **Diseases:** Ewing sarcoma (MONDO:0012817)

## Full-text entities

- **Diseases:** Gastrointestinal Bleeding (MESH:D006471), neoplasm (MESH:D009369), melena (MESH:D008551), Ewing sarcoma (MESH:D012512), bowel obstruction (MESH:D012778), malignant tumor of bone (MESH:D001859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11055616/full.md

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Source: https://tomesphere.com/paper/PMC11055616