A Case of Multidomain Integrated Treatment Strategy for Complex Primary Pulmonary Sarcomatoid Carcinoma

TL;DR

This paper presents a case of a rare aggressive lung tumor treated with a combined approach, significantly improving the patient's survival.

Contribution

The novel contribution is the successful use of a multidomain integrated treatment strategy for complex primary pulmonary sarcomatoid carcinoma.

Findings

The patient had a 90% central airway obstruction due to primary PSC.

Combined vascular and bronchoscopic interventions prolonged survival by 19 months.

The treatment approach offers a potential clinical reference for managing advanced PSC.

Abstract

肺肉瘤样癌（pulmonary sarcomatoid carcinoma, PSC）是一类罕见的、恶性程度较高的肺部肿瘤，分为多形性癌、梭形细胞癌、巨细胞癌、癌肉瘤和肺母细胞瘤5种病理类型。PSC发病隐匿，临床症状和体征无特异性，与肿瘤生长和侵袭部位密切相关，可表现为刺激性咳嗽、痰中带血丝、呼吸困难或胸痛等。PSC易早期出现转移，多数患者就诊时已是局部进展期或晚期，中位生存时间为9个月。我呼吸病中心诊治1例致中央气道狭窄90%的原发性PSC患者；通过血管介入和气管镜下介入联合治疗的方法拯救了患者生命，延长了生存时间，术后随访19个月，效果满意，现报道如下，以供临床借鉴。

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