# A Case of Multidomain Integrated Treatment Strategy for Complex Primary Pulmonary Sarcomatoid Carcinoma

**Authors:** Xiaosen HUO, Hang ZOU, Yanyan DONG, Yuan LI, Lingjie BIAN, Lei LI, Hongwu WANG

PMC · DOI: 10.3779/j.issn.1009-3419.2024.102.04 · 2024-02-20

## TL;DR

This paper presents a case of a rare aggressive lung tumor treated with a combined approach, significantly improving the patient's survival.

## Contribution

The novel contribution is the successful use of a multidomain integrated treatment strategy for complex primary pulmonary sarcomatoid carcinoma.

## Key findings

- The patient had a 90% central airway obstruction due to primary PSC.
- Combined vascular and bronchoscopic interventions prolonged survival by 19 months.
- The treatment approach offers a potential clinical reference for managing advanced PSC.

## Abstract

肺肉瘤样癌（pulmonary sarcomatoid carcinoma, PSC）是一类罕见的、恶性程度较高的肺部肿瘤，分为多形性癌、梭形细胞癌、巨细胞癌、癌肉瘤和肺母细胞瘤5种病理类型。PSC发病隐匿，临床症状和体征无特异性，与肿瘤生长和侵袭部位密切相关，可表现为刺激性咳嗽、痰中带血丝、呼吸困难或胸痛等。PSC易早期出现转移，多数患者就诊时已是局部进展期或晚期，中位生存时间为9个月。我呼吸病中心诊治1例致中央气道狭窄90%的原发性PSC患者；通过血管介入和气管镜下介入联合治疗的方法拯救了患者生命，延长了生存时间，术后随访19个月，效果满意，现报道如下，以供临床借鉴。

## Full-text entities

- **Diseases:** metastasize (MESH:D009362), carcinosarcoma (MESH:D002296), giant cell carcinoma (MESH:D018286), cough (MESH:D003371), spindle cell carcinoma (MESH:D002277), pulmonary blastoma (MESH:D018202), PSC (MESH:D002292), dyspnea (MESH:D004417), chest pain (MESH:D002637), pleomorphic carcinoma (MESH:D008949), tumor (MESH:D009369), stenosis in central airway (MESH:D003251)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10918249/full.md

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Source: https://tomesphere.com/paper/PMC10918249