Betacoronavirus Infection Outbreak, São Paulo, Brazil, Fall 2023
Tânia do Socorro Souza Chaves, Ana H. Perosa, Gabriela Barbosa, Diogo B. Ferreira, Nancy Bellei

TL;DR
A human coronavirus OC43 outbreak occurred in São Paulo, Brazil, after SARS-CoV-2 cases declined, affecting patients and healthcare workers.
Contribution
The study highlights the importance of routine surveillance for detecting coronavirus infections in healthcare settings.
Findings
Human coronavirus OC43 caused an outbreak after SARS-CoV-2 cases disappeared.
Infection was linked to healthcare workers in nearly 30% of patients.
Routine surveillance improved detection of coronaviruses in healthcare professionals and patients.
Abstract
We report a human coronavirus OC43 infection outbreak in hospitalized patients and healthcare workers in São Paulo, Brazil, occurring after SARS-CoV-2 cases disappeared. Infection was associated with healthcare workers in 5 (29.4%) patients. Routine surveillance including a respiratory virus panel can improve coronavirus detection in both healthcare professionals and patients.
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Taxonomy
TopicsCOVID-19 Clinical Research Studies · SARS-CoV-2 and COVID-19 Research · SARS-CoV-2 detection and testing
