# Betacoronavirus Infection Outbreak, São Paulo, Brazil, Fall 2023

## TL;DR

A human coronavirus OC43 outbreak occurred in São Paulo, Brazil, after SARS-CoV-2 cases declined, affecting patients and healthcare workers.

## Contribution

The study highlights the importance of routine surveillance for detecting coronavirus infections in healthcare settings.

## Key findings

- Human coronavirus OC43 caused an outbreak after SARS-CoV-2 cases disappeared.
- Infection was linked to healthcare workers in nearly 30% of patients.
- Routine surveillance improved detection of coronaviruses in healthcare professionals and patients.

## Abstract

We report a human coronavirus OC43 infection outbreak in hospitalized patients and healthcare workers in São Paulo, Brazil, occurring after SARS-CoV-2 cases disappeared. Infection was associated with healthcare workers in 5 (29.4%) patients. Routine surveillance including a respiratory virus panel can improve coronavirus detection in both healthcare professionals and patients.