Methicillin-Resistant Staphylococcus aureus Cellulitis Causing Meningitis From Hematogenous Dissemination: A Case Report
Omar M Masarweh, Suhail Saad-Omer, Michael Rohr, Neha Meda, Nicole Brenner

TL;DR
A rare case of methicillin-resistant Staphylococcus aureus meningitis caused by bloodstream infection from a diabetic foot infection is reported and successfully treated.
Contribution
This case report highlights a rare hematogenous route of methicillin-resistant Staphylococcus aureus causing meningitis.
Findings
MRSA meningitis can result from hematogenous spread via bacteremia.
A diabetic foot infection led to bloodstream infection and multiple complications including meningitis.
Treatment with intravenous daptomycin and rifampin was successful.
Abstract
Methicillin-resistant Staphylococcus aureus meningitis is commonly associated with surgical procedures that closely interact with the central nervous system; however, hematogenous spread via bacteremia is rarely reported. Here, we present a case of methicillin-resistant Staphylococcus aureus meningitis as a complication of a diabetic foot infection that disseminated into a bloodstream infection causing infective endocarditis, discitis, vertebral osteomyelitis, and meningitis that was successfully treated with intravenous daptomycin and rifampin.
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Taxonomy
TopicsAntimicrobial Resistance in Staphylococcus · Bacterial Infections and Vaccines · Infective Endocarditis Diagnosis and Management
