Serum albumin adjusted calcium and fluoride among type 2 diabetes mellitus patients
Shruti Divya Dubey, Shashidhar Kurpad Nagaraj, Harish Rangareddy
TL;DR
The paper explores how calcium and fluoride levels are affected in patients with type 2 diabetes, focusing on the role of serum albumin in calcium regulation.
Contribution
The study introduces the importance of adjusting calcium measurements for serum albumin in T2DM patients.
Findings
Calcium homeostasis disruptions may contribute to insulin dysfunction in T2DM.
Fluoride metabolism changes may occur due to impaired renal function in T2DM patients.
Serum albumin levels significantly affect accurate calcium estimation in these patients.
Abstract
The regulation of glucose-dependent insulin secretion in pancreatic β-cells relies on calcium concentration, making it a calcium-dependent process. Disruptions in calcium homeostasis may contribute to insulin dysfunction and disturbances in glucose homeostasis, potentially playing a role in the development of type 2 diabetes mellitus (T2DM). In T2DM patients, there may be changes in fluoride metabolism due to impaired renal function. Measurement of serum albumin-adjusted calcium and is crucial since changes in albumin levels can impact the accurate estimation of true calcium.
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Taxonomy
TopicsDiet and metabolism studies · Folate and B Vitamins Research · Parathyroid Disorders and Treatments