TL;DR
The paper shows that RIPK3 activation leads to neuronal death in mice after brain hemorrhage, highlighting a potential target for treatment.
Contribution
The study identifies RIPK3 and DAXX as key players in neuronal necroptosis following intracerebral hemorrhage in mice.
Findings
RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage.
Inhibiting RIPK3 reduces neuronal death in mice with brain hemorrhage.
Abstract
The cover image is based on the Research Article RIPK3 activation promotes DAXX‐dependent neuronal necroptosis after intracerebral hemorrhage in mice by Qingqing Bai et al., https://doi.org/10.1111/cns.14397.
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Taxonomy
TopicsIntracerebral and Subarachnoid Hemorrhage Research · S100 Proteins and Annexins · Cell death mechanisms and regulation