# Additional Cover

PMC · DOI: 10.1111/cns.14626 · CNS Neuroscience & Therapeutics · 2024-01-28

## TL;DR

The paper shows that RIPK3 activation leads to neuronal death in mice after brain hemorrhage, highlighting a potential target for treatment.

## Contribution

The study identifies RIPK3 and DAXX as key players in neuronal necroptosis following intracerebral hemorrhage in mice.

## Key findings

- RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage.
- Inhibiting RIPK3 reduces neuronal death in mice with brain hemorrhage.

## Abstract

The cover image is based on the Research Article RIPK3 activation promotes DAXX‐dependent neuronal necroptosis after intracerebral hemorrhage in mice by Qingqing Bai et al., https://doi.org/10.1111/cns.14397.

## Linked entities

- **Genes:** RIPK3 (receptor interacting serine/threonine kinase 3) [NCBI Gene 11035], DAXX (death domain associated protein) [NCBI Gene 1616]
- **Species:** Mus musculus (taxon 10090)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10823045/full.md

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Source: https://tomesphere.com/paper/PMC10823045