TL;DR
This paper explores how IFN-γ helps regenerate progenitor cells in the cerebellum after radiation by boosting Shh ligand production.
Contribution
The study reveals a novel mechanism involving IFN-γ and Shh ligand in promoting progenitor cell regeneration post-radiation.
Findings
IFN-γ promotes the regeneration of Nestin-expressing progenitor cells in the cerebellum.
This regeneration is achieved by increasing Shh ligand production.
The process is crucial for recovery in the developing cerebellum after radiation.
Abstract
The cover image is based on the Original Article IFN‐γ promotes radioresistant Nestin‐expressing progenitor regeneration in the developing cerebellum by augmenting Shh ligand production by Jian Hu et al., https://doi.org/10.1111/cns.14485.
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Taxonomy
TopicsNeurogenesis and neuroplasticity mechanisms · Fetal and Pediatric Neurological Disorders · Pluripotent Stem Cells Research