# Additional Cover

PMC · DOI: 10.1111/cns.14622 · CNS Neuroscience & Therapeutics · 2024-01-28

## TL;DR

This paper explores how IFN-γ helps regenerate progenitor cells in the cerebellum after radiation by boosting Shh ligand production.

## Contribution

The study reveals a novel mechanism involving IFN-γ and Shh ligand in promoting progenitor cell regeneration post-radiation.

## Key findings

- IFN-γ promotes the regeneration of Nestin-expressing progenitor cells in the cerebellum.
- This regeneration is achieved by increasing Shh ligand production.
- The process is crucial for recovery in the developing cerebellum after radiation.

## Abstract

The cover image is based on the Original Article IFN‐γ promotes radioresistant Nestin‐expressing progenitor regeneration in the developing cerebellum by augmenting Shh ligand production by Jian Hu et al., https://doi.org/10.1111/cns.14485.

## Linked entities

- **Proteins:** IFNG (interferon gamma), SHH (sonic hedgehog signaling molecule)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10823042/full.md

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Source: https://tomesphere.com/paper/PMC10823042