Stimulated low-frequency Raman scattering in albumin

TL;DR

This study demonstrates the use of stimulated low-frequency Raman scattering to investigate the elastic properties and vibrational modes of albumin, providing a new method for biological nanostructure analysis.

Contribution

First-time application of stimulated low-frequency Raman scattering to analyze vibrational modes in human and bovine serum albumin.

Findings

Measured eigenfrequencies of albumin nanoparticles.

Determined conversion efficiency and threshold for Raman scattering.

Identified potential for biological object identification.

Abstract

Stimulated low-frequency Raman scattering can give essential information about the elastic properties of different nanoparticles systems, in particular, biological nanostructures. In the present study, low-frequency vibrational modes in human and bovine serum albumin were for the first time investigated using stimulated low-frequency Raman scattering. Stimulated low-frequency Raman scattering frequency shifts, corresponding to acoustic eigenfrequencies of the sample, were registered by Fabri-Perot interferometers. Conversion efficiency, threshold and set of eigenfrequencies were also measured. Stimulated low-frequency Raman scattering can be applied for biological objects identification and impact on them.