# Stimulated low-frequency Raman scattering in albumin

**Authors:** M.A. Shevchenko, L.L. Chaikov, M.N. Kirichenko, A.D. Kudryavtseva,, T.V. Mironova, V.I. Savichev, V.V. Sokovishin, N.V. Tcherniega, K.I. Zemskov

arXiv: 1902.10456 · 2019-02-28

## TL;DR

This study demonstrates the use of stimulated low-frequency Raman scattering to investigate the elastic properties and vibrational modes of albumin, providing a new method for biological nanostructure analysis.

## Contribution

First-time application of stimulated low-frequency Raman scattering to analyze vibrational modes in human and bovine serum albumin.

## Key findings

- Measured eigenfrequencies of albumin nanoparticles.
- Determined conversion efficiency and threshold for Raman scattering.
- Identified potential for biological object identification.

## Abstract

Stimulated low-frequency Raman scattering can give essential information about the elastic properties of different nanoparticles systems, in particular, biological nanostructures. In the present study, low-frequency vibrational modes in human and bovine serum albumin were for the first time investigated using stimulated low-frequency Raman scattering. Stimulated low-frequency Raman scattering frequency shifts, corresponding to acoustic eigenfrequencies of the sample, were registered by Fabri-Perot interferometers. Conversion efficiency, threshold and set of eigenfrequencies were also measured. Stimulated low-frequency Raman scattering can be applied for biological objects identification and impact on them.

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Source: https://tomesphere.com/paper/1902.10456