Rate Equation Approaches to Amplification of Enantiomeric Excess and Chiral Symmetry Breaking

TL;DR

This paper reviews rate equation models of the Soai reaction, explaining how autocatalytic processes can lead to either enantiomeric excess amplification or chiral symmetry breaking, with implications for life's homochirality.

Contribution

It clarifies the conditions under which autocatalytic reactions produce enantiomeric excess or chiral symmetry breaking, highlighting the role of reversibility and recycling processes.

Findings

Enantiomeric excess amplification occurs in irreversible reactions.

Chiral symmetry breaking requires reversible reactions with recycling.

Flow diagrams in phase space illustrate different behaviors.

Abstract

Theoretical models and rate equations relevant to the Soai reaction are reviewed. It is found that in a production of chiral molecules from an achiral substrate autocatalytic processes can induce either enantiomeric excess (ee) amplification or chiral symmetry breaking. Former terminology means that the final ee value is larger than the initial value but depends on this, whereas the latter means the selection of a unique value of the final ee, independent of the initial value. The ee amplification takes place in an irreversible reaction such that all the substrate molecules are converted to chiral products and the reaction comes to a halt. The chiral symmetry breaking is possible when recycling processes are incorporated. Reactions become reversible and the system relaxes slowly to a unique final state. The difference between the two behaviors is apparent in the flow diagram in the phase space of chiral molecule concentrations. The ee amplification takes place when the flow terminates on a line of fixed points (or a fixed line), whereas symmetry breaking corresponds to the dissolution of the fixed line accompanied by the appearance of fixed points. Relevance of the Soai reaction to the homochirality in life is also discussed.