Accurate measurement of ^{13}C - ^{15}N distances with solid-state NMR

TL;DR

This paper presents a solid-state NMR method for accurately measuring hetero-nuclear distances in static powder samples, demonstrated on glycine with high precision.

Contribution

It introduces a two-dimensional single-echo NMR scheme with adiabatic cross-polarization for precise distance measurements.

Findings

Measured ^13C-^15N distances in glycine with high accuracy

Demonstrated method's effectiveness on crystalline samples

Achieved distance measurements with sub-angstrom precision

Abstract

Solid-state NMR technique for measureing distances between hetero-nuclei in static powder samples is described. It is based on a two-dimensional single-echo scheme enhanced with adiabatic cross-polarization. As an example, the results for intra-molecular distances in $\alpha$-crystalline form of glycine are presented. The measured NMR distances ^13 C(2) - ^15 N and ^13 C(1) - ^15 N are 1.496 $\pm$ 0.002 \AA and 2.50 $\pm$ 0.02 \AA, respectively.