From Intracellular Traffic to a Novel Class of Driven Lattice Gas Models

TL;DR

This paper reviews the modeling of intracellular transport using driven lattice gas models, focusing on how coupling with bulk kinetics affects phase behavior and system properties.

Contribution

It introduces a novel class of driven lattice gas models incorporating Langmuir kinetics, revealing new phase diagram features and multi-phase coexistence phenomena.

Findings

Coupling with Langmuir kinetics alters phase diagrams.

Identification of multi-phase coexistence regions.

Analysis of topological changes in system behavior.

Abstract

Motor proteins are key players in intracellular transport processes and biological motion. Theoretical modeling of these systems has been achieved by the use of step processes on one-dimensional lattices. After a comprehensive introduction to the total asymmetric exclusion process and some analytical tools, we will give a review on different lines of research attracted to the aspects of this systems. We will focus on the generic properties of a coupling between the exclusion process and Langmuir bulk kinetics that induce topological changes in the phase diagram and multi-phase coexistence.