Dielectrophoresis of nanoscale dsDNA and humidity effects on its electrical conductivity
S. Tuukkanen, A. Kuzyk, J. J. Toppari, V. P. Hytonen, T. Ihalainen, P., Torma

TL;DR
This paper presents a dielectrophoresis technique for trapping nanoscale DNA molecules, enabling conductivity measurements that reveal moisture-dependent electrical behavior at the single-molecule level.
Contribution
It introduces a novel dielectrophoresis method for single-molecule DNA trapping and investigates humidity effects on DNA conductivity.
Findings
DNA is insulating when dry
Moisture increases DNA conductivity
Conformation influences electrical properties
Abstract
The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the single molecule level. Electrical conductivity of individual 140-nm-long DNA molecules was measured, showing insulating behavior in dry conditions. In contrast, clear enhancement of conductivity was observed in moist conditions, relating to the interplay between the conformation of DNA molecules and their conductivity.
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