# Conjugated Linoleic Acid and Its Beneficial Effects in Obesity, Cardiovascular Disease, and Cancer

**Authors:** Sanjay Basak, Asim K. Duttaroy

PMC · DOI: 10.3390/nu12071913 · Nutrients · 2020-06-28

## Full-text entities

- **Genes:** MMP9 (matrix metallopeptidase 9) [NCBI Gene 4318] {aka CLG4B, GELB, MANDP2, MMP-9}, VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}, MMP2 (matrix metallopeptidase 2) [NCBI Gene 4313] {aka CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1}, MMP3 (matrix metallopeptidase 3) [NCBI Gene 4314] {aka CHDS6, MMP-3, SL-1, STMY, STMY1, STR1}, PPARG (peroxisome proliferator activated receptor gamma) [NCBI Gene 5468] {aka CIMT1, FPLD3, GLM1, NR1C3, PPARG1, PPARG2}, ADIPOQ (adiponectin, C1Q and collagen domain containing) [NCBI Gene 9370] {aka ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1}, LPL (lipoprotein lipase) [NCBI Gene 4023] {aka HDLCQ11, LIPD}, FASN (fatty acid synthase) [NCBI Gene 2194] {aka FAS, OA-519, SDR27X1}, KDR (kinase insert domain receptor) [NCBI Gene 3791] {aka CD309, FLK1, VEGFR, VEGFR2}, LEP (leptin) [NCBI Gene 3952] {aka LEPD, OB, OBS}, PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2) [NCBI Gene 5563] {aka AMPK, AMPK2, AMPKa2, PRKAA}, NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, BCL2 (BCL2 apoptosis regulator) [NCBI Gene 596] {aka Bcl-2, PPP1R50}, CASP3 (caspase 3) [NCBI Gene 836] {aka CPP32, CPP32B, SCA-1}, IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}
- **Diseases:** rhinovirus infection (MESH:D007239), abdominal adiposity (MESH:D000007), laryngeal papillomatosis (MESH:C537876), arthritis (MESH:D001168), inflammatory bowel disease (MESH:D015212), hepatic steatosis (MESH:D005234), carcinogenic (MESH:D011230), atherogenic (MESH:D050197), Crohn's disease (MESH:D003424), colon cancer (MESH:D015179), adiposity (MESH:D018205), inflammation (MESH:D007249), Obesity (MESH:D009765), hypercholesterolemic (MESH:D006938), hypertension (MESH:D006973), CVD (MESH:D002318), breast cancer (MESH:D001943), myocardial infarction (MESH:D009203), asthmatics (MESH:D013224), airway obstruction (MESH:D000402), rectal cancer (MESH:D012004), rheumatoid arthritis (MESH:D001172), atopic dermatitis (MESH:D003876), Cancer (MESH:D009369), hypersensitivity (MESH:D004342)
- **Chemicals:** c9t11-CLA (MESH:C503589), calcium (MESH:D002118), t10c12-CLA (MESH:C496197), vegetable oils (MESH:D010938), trans fat (MESH:D044242), lipid (MESH:D008055), docosahexaenoic acid (MESH:D004281), prostaglandin (MESH:D011453), n-6 fatty acid (MESH:D043371), vitamin E (MESH:D014810), Fatty acids (MESH:D005227), n-3 fatty acids (MESH:D015525), glutamate (MESH:D018698), polyunsaturated fatty acid (MESH:D005231), triacylglycerol (MESH:D014280), 9c11t-CLA (-), CLA (MESH:D044243),  (MESH:D004041),  (MESH:D020011)
- **Species:** Bos taurus (bovine, species) [taxon 9913], Mus musculus (house mouse, species) [taxon 10090], Rattus norvegicus (brown rat, species) [taxon 10116], Cricetinae (hamsters, subfamily) [taxon 10026], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC7401241/full.md

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Source: https://tomesphere.com/paper/PMC7401241