# Primary jejunal gastrinoma: a case report and review of the literature

**Authors:** Kevin A. Wang, Yenn-Hwei Chou, Shu-Han Huang, Tong-Jong Chen

PMC · DOI: 10.1186/s12957-015-0728-x · World Journal of Surgical Oncology · 2015-11-06

## TL;DR

A rare case of a jejunal gastrinoma was successfully treated with surgery, leading to long-term remission.

## Contribution

This report adds a new case of primary jejunal gastrinoma with a 10-year disease-free follow-up.

## Key findings

- Surgical resection of a primary jejunal gastrinoma resulted in eugastrinemia.
- The patient remained disease-free for 10 years after surgery.
- Primary jejunal gastrinomas without metastasis may have a good prognosis after resection.

## Abstract

Primary jejunal gastrinomas are exceedingly rare, and data for long-term follow-up is limited. Until now, only six cases of gastrinomas arising from the jejunum have been reported in the English literature.

Presented is a case of a primary gastrinoma located in the proximal jejunum. After surgical resection of the tumor, eugastrinemia was quickly achieved and after a 10-year follow-up period, the patient was still disease-free.

This case report demonstrates that surgical resection of a primary jejunal gastrinoma without evidence of metastasis can be curative, with a good long-term prognosis.

## Linked entities

- **Diseases:** gastrinoma (MONDO:0003523)

## Full-text entities

- **Genes:** GAST (gastrin) [NCBI Gene 2520] {aka GAS}, AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}, CEACAM3 (CEA cell adhesion molecule 3) [NCBI Gene 1084] {aka CD66D, CEA, CGM1, CGM1a, W264, W282}
- **Diseases:** ZES (MESH:D015043), neuroendocrine tumor (MESH:D018358), jejunal ulcers (MESH:D007579), jejunal tumor (MESH:D007580), hemorrhage (MESH:D006470), abdominal discomfort (MESH:D000007), liver metastases (MESH:D009362), Gastrinomas of the jejunum (MESH:D015408), peptic ulceration (MESH:D010437), gastroesophageal reflux disease (MESH:D005764), acid regurgitation (MESH:D008944), non-beta islet cell tumor (MESH:D007516), ulcers (MESH:D014456), esophageal, gastric, duodenal, and (MESH:D004932), SRS (MESH:D013734), diarrhea (MESH:D003967), nodes (MESH:D012804), Tumor (MESH:D009369), lymph node metastasis (MESH:D008207), weight loss (MESH:D015431), Gastric ulcers (MESH:D013276), heartburn (MESH:D006356), erosions (MESH:D014077)
- **Chemicals:** Hematoxylin and eosin (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** TC — Rattus norvegicus (Rat), Adenocarcinoma of the rat prostate, Cancer cell line (CVCL_L303)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4636740/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC4636740/full.md

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Source: https://tomesphere.com/paper/PMC4636740