# Tourette Syndrome research highlights 2014 **Authors:** Cheryl A Richards, Kevin J Black, Barbara Coffey, Kevin J Black, Davide Martino, Kevin J Black PMC · DOI: 10.12688/f1000research.6209.1 · 2015-03-16 ## TL;DR This paper summarizes key 2014 research on Tourette syndrome and tic disorders, covering both animal and human studies. ## Contribution The paper provides a curated overview of significant 2014 research findings on Tourette syndrome and related tic disorders. ## Key findings - The paper highlights important 2014 studies on Tourette syndrome and tic disorders. - It includes a range of research from animal models to human studies. - Readers are encouraged to provide feedback or share their own favorite studies. ## Abstract About 200 journal articles reported research on Tourette syndrome and other tic disorders in 2014. Here we briefly summarize a few of the reports that seemed most important or interesting, ranging from animal models to human studies. Readers can comment on our choices or provide their own favorites using the tools on the online article. ## Linked entities - **Diseases:** Tourette syndrome (MONDO:0007661) ## Full-text entities - **Genes:** HDC (histidine decarboxylase) [NCBI Gene 3067], SMN1 (survival of motor neuron 1, telomeric) [NCBI Gene 6606] {aka BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3}, Hdc (histidine decarboxylase) [NCBI Gene 15186] {aka Hdc-a, Hdc-c, Hdc-e, Hdc-s}, Drd2 (dopamine receptor D2) [NCBI Gene 13489] {aka D2R, Drd-2} - **Diseases:** DBS (MESH:D001927), body-focused repetitive disorder (MESH:D057215), Rett's syndrome (MESH:D015518), compulsions (MESH:D000073932), movement disorders (MESH:D009069), jerks (MESH:D009207), Tourette[AU (MESH:C566303), Mov Disord (MESH:D009358), head twitches (MESH:D006258), weight gain (MESH:D015430), Tic Disorders (MESH:D013981), CTD (MESH:C563241), PUTS (MESH:D020323), Psychiatric Disorders (MESH:D001523), blinking (MESH:D000092164), Tardive dyskinesia (MESH:D004409), OCD (MESH:D009771), neuroinflammation (MESH:D000090862), SMA syndromes (MESH:D017034), hyperactivity (MESH:D006948), TS (MESH:D005879), ADHD (MESH:D001289), anxiety (MESH:D001007), startle (MESH:D016750), primary dystonia (MESH:D020821) - **Chemicals:** GABA (MESH:D005680), Fluphenazine (MESH:D005476), amphetamine (MESH:D000661), histidine (MESH:D006639), d-amphetamine (MESH:D003913), haloperidol (MESH:D006220), ecopipam (MESH:C058081), dopamine (MESH:D004298), histamine (MESH:D006632), bicuculline (MESH:D001640), D2 antagonists (-) - **Species:** Mus musculus (house mouse, species) [taxon 10090], Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606] ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC4602330/full.md --- Source: https://tomesphere.com/paper/PMC4602330