# The many-faced KSR1: a tumor suppressor in breast cancer **Authors:** Hua Zhang, Justin Stebbing, Georgios Giamas PMC · DOI: 10.18632/oncoscience.219 · Oncoscience · 2015-08-25 ## Full-text entities - **Genes:** MAP2K7 (mitogen-activated protein kinase kinase 7) [NCBI Gene 5609] {aka JNKK2, MAPKK7, MEK, MEK 7, MKK7, PRKMK7}, BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}, KSR1 (kinase suppressor of ras 1) [NCBI Gene 8844] {aka KSR, RSU2}, Kras (Kras proto-oncogene, GTPase) [NCBI Gene 16653] {aka K-Ras, K-Ras 2, K-ras, Ki-ras, Kras-2, Kras2}, Brca1 (breast cancer 1, early onset) [NCBI Gene 12189], Bard1 (BRCA1 associated RING domain 1) [NCBI Gene 12021], TP53 (tumor protein p53) [NCBI Gene 7157] {aka BCC7, BMFS5, LFS1, P53, TRP53}, MAPK1 (mitogen-activated protein kinase 1) [NCBI Gene 5594] {aka ERK, ERK-2, ERK2, ERT1, MAPK2, NS13}, RAF1 (Raf-1 proto-oncogene, serine/threonine kinase) [NCBI Gene 5894] {aka CMD1NN, CRAF, NS5, Raf-1, c-Raf}, ZHX2 (zinc fingers and homeoboxes 2) [NCBI Gene 22882] {aka AFR1, RAF}, SIRT1 (sirtuin 1) [NCBI Gene 23411] {aka SIR2, SIR2L1, SIR2alpha}, CCAR2 (cell cycle and apoptosis regulator 2) [NCBI Gene 57805] {aka DBC-1, DBC1, KIAA1967, NET35, p30 DBC, p30DBC}, Ksr1 (kinase suppressor of ras 1) [NCBI Gene 16706] {aka B-KSR1, D11Bhm183e, D11Bhm184e, Ksr, RSU2, hb}, BARD1 (BRCA1 associated RING domain 1) [NCBI Gene 580], CHEK1 (checkpoint kinase 1) [NCBI Gene 1111] {aka CHK1, OZEMA21}, Zhx2 (zinc fingers and homeoboxes 2) [NCBI Gene 387609] {aka Afr-1, Afr1, Raf, mKIAA0854} - **Diseases:** pancreatic and lung cancer (MESH:D008175), tumorigenesis (MESH:D063646), cancer (MESH:D009369), skin, pancreatic and lung carcinomas (MESH:C562463), breast cancer (MESH:D001943) - **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC4580053/full.md ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC4580053/full.md ## References 8 references — full list in the complete paper: https://tomesphere.com/paper/PMC4580053/full.md --- Source: https://tomesphere.com/paper/PMC4580053