# An Unusual MRI Appearance of Osseous Metastases

**Authors:** Konstantin Boroda, Ammar Chaudhry, Gary Clarke, Yudell Edelstein

PMC · DOI: 10.7759/cureus.300 · Cureus · 2015-08-11

## TL;DR

This paper describes a rare MRI appearance of bone metastases that resembled a different condition, helping to improve their identification.

## Contribution

The paper presents a previously unreported lamellated MRI appearance of osseous metastases.

## Key findings

- MRI showed multiple lamellated lesions in the distal femur, confirmed as metastatic disease.
- The appearance was initially mistaken for CPPD arthropathy based on radiographic and CT findings.
- This case highlights the importance of recognizing unusual metastatic appearances for accurate diagnosis.

## Abstract

Bone metastases can present in a wide variety of appearances across all imaging modalities. We present a unique appearance of a distal femoral metastasis in a patient who initially complained of knee pain. The radiographic and CT findings were initially suspicious for calcium pyrophosphate deposition (CPPD) arthropathy; however, an MRI demonstrated multiple lesions with a lamellated appearance confirmed on biopsy to be metastatic disease. This unusual lamellated appearance has not been previously described. We present this case to help distinguish this entity radiographically and better classify this finding as a manifestation of metastatic disease.

## Linked entities

- **Diseases:** metastatic disease (MONDO:0024883)

## Full-text entities

- **Genes:** CEACAM3 (CEA cell adhesion molecule 3) [NCBI Gene 1084] {aka CD66D, CEA, CGM1, CGM1a, W264, W282}
- **Diseases:** lumbar degenerative disc disease (MESH:D055959), soft tissue injury (MESH:D017695), hemarthrosis (MESH:D006395), lung lesions (MESH:D008171), neoplastic disease (MESH:D004194), Sjogren's syndrome (MESH:D012859), carcinoma polyarthritis (MESH:D001168), hypoglycemic (MESH:C000721848), gout (MESH:D006073), bone lesions (MESH:D001847), Lung carcinoma (MESH:D008175), cerebral vascular accidents (MESH:D020521), hyperlipidemia (MESH:D006949), breast (MESH:D061325), CPPD arthropathy (MESH:D002805), Multiple myeloma (MESH:D009101), prostate (MESH:D011472), bony lesions (MESH:D000070896), hypertension (MESH:D006973), paraneoplastic syndromes (MESH:D010257), POEMS syndrome (MESH:D016878), Knee pain (MESH:D046788), calcification (MESH:D002114), Lymphoma (MESH:D008223), leukemia (MESH:D007938), bronchogenic carcinoma (MESH:D002283), primary tumor (MESH:D001932), joint effusion (MESH:D000080324), tenderness (MESH:D063806), arthritic type pain (MESH:D010146), adenocarcinoma (MESH:D000230), Bone metastases (MESH:D009362), Bronchial cancers (MESH:D009369), sclerosis (MESH:D012598), edema (MESH:D004487), hypertrophic osteoarthropathy (MESH:D010004), necrotic bone (MESH:D010020), carcinomatous arthritis (MESH:D055756), diabetes mellitus (MESH:D003920), Metastatic disease (MESH:D000092182), intramedullary lesion (MESH:D013120)
- **Chemicals:** Hematoxylin (MESH:D006416), eosin (MESH:D004801), calcium pyrophosphate (MESH:D002131), technetium-99 (MESH:C000615519)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC4571901/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4571901/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC4571901/full.md

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Source: https://tomesphere.com/paper/PMC4571901