# Primo-Vascular System as Presented by Bong Han Kim

**Authors:** Vitaly Vodyanoy, Oleg Pustovyy, Ludmila Globa, Iryna Sorokulova

PMC · DOI: 10.1155/2015/361974 · Evidence-based Complementary and Alternative Medicine : eCAM · 2015-08-25

## TL;DR

This paper reveals the staining methods used by Bong Han Kim in his discovery of a new vascular system linked to tissue regeneration.

## Contribution

The paper discloses the specific staining protocols used by Kim, which were previously not detailed in his original work.

## Key findings

- Bong Han Kim's staining methods were based on well-established protocols from the mid-20th century.
- The disclosed methods help clarify how Kim differentiated the primo-vascular system from blood and lymph systems.
- The study provides insight into Kim's approach to characterizing the system's nodes and vessels.

## Abstract

In the 1960s Bong Han Kim discovered and characterized a new vascular system. He was able to differentiate it clearly from vascular blood and lymph systems by the use of a variety of methods, which were available to him in the mid-20th century. He gave detailed characterization of the system and created comprehensive diagrams and photographs in his publications. He demonstrated that this system is composed of nodes and vessels, and it was responsible for tissue regeneration. However, he did not disclose in detail his methods. Consequently, his results are relatively obscure from the vantage point of contemporary scientists. The stains that Kim used had been perfected and had been in use for more than 100 years. Therefore, the names of the stains were directed to the explicit protocols for the usage with the particular cells or molecules. Traditionally, it was not normally necessary to describe the method used unless it is significantly deviated from the original method. In this present work, we have been able to disclose staining methods used by Kim.

## Full-text entities

- **Genes:** Star (steroidogenic acute regulatory protein) [NCBI Gene 20845] {aka D8Ertd419e, stARD1}
- **Diseases:** liver (MESH:D017093), Congenital Jing (MESH:D008209), pain (MESH:D010146), inflammatory (MESH:D007249), leukemia (MESH:D007938), Fibers (MESH:D000071075), diabetes (MESH:D003920), Cancer (MESH:D009369), PVS (MESH:D057772), necrotic (MESH:D009336), bone marrow (MESH:D001855), hemorrhage (MESH:D006470), anemia (MESH:D000740)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615], Mus musculus (house mouse, species) [taxon 10090], Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4562093/full.md

## References

88 references — full list in the complete paper: https://tomesphere.com/paper/PMC4562093/full.md

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Source: https://tomesphere.com/paper/PMC4562093